R0182

Ribavirin

CAS number 36791-04-5
Molecular weight C8H12N4O5 = 244.2
Assay > 98 %

Ribavirin is a synthetic nucleoside analogue structurally related to guanine. Ribavirine inhibits the replication of a wide range of RNA and DNA viruses. The antiviral mechanism of action of Ribavirin is not fully defined, but relates to alteration of cellular nucleotide pools and inhibition of viral mRNA synthesis. Intracellular phosphorylation of ribavirin into phosphate derivatives is mediated by host cell enzymes. Ribavirin monophosphates competatively inhibit cellular inosine-5’-phosphate dehydrogenase and interfere with the synthesis of guanosine triphospha-te (GTP) and thus nucleic acid synthesis in general. Ribavirin triphosphate also competively inhibits the GTP dependent 5’-capping of viral mRNA.

Storage condition

  • Store at room temperature
  • Freely soluble in water

Hazard statements

  • H360 May damage fertility or the unborn child

Precautionary statements

  • P201 Obtain special instructions before use
  • P281 Use personal protective equipment as required
  • P308 IF exposed or concerned:
  • P313 Get medical advice/attention
Filename Language File size
R0182_GB.pdf English 146 KB
R0182_NL.pdf Nederlands 150 KB
R0182_DE.pdf Deutsch 155 KB
R0182_FR.pdf Français 151 KB
R0182_ES.pdf Español 151 KB
R0182_IT.pdf Italiano 149 KB
Filename Batch number Expiry date Language
R0182_012063_GB.pdf 012063 04-2019 English
Contact us if your Certificate of Analysis is not listed here.
  • R0182.0250
  • 250 mg
  • € 19.60
  • Order
  • R0182.1000
  • 1 g
  • € 54.70
  • Order
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